Alta Partners NextGen Fund II Management, LLC - Sep 17, 2021 Form 4 Insider Report for Tyra Biosciences, Inc. (TYRA)

Role: 10%+ Owner
Signature: /s/ Daniel S. Janney, Manager of the Alta Partners NextGen Fund II Management, LLC, the General Partner of the Alta Partners NextGen Fund II, L.P.
Stock symbol: TYRA
Transactions as of: Sep 17, 2021
Transactions value $: $2,500,000
Form type: 4
Date filed: 9/17/2021, 04:47 PM
Previous filing: Sep 14, 2021

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	TYRA	Common Stock	Conversion of derivative security		+3.81M	+3374.79%		3.92M	Sep 17, 2021	See footnote	F1, F2
transaction	TYRA	Common Stock	Purchase	$2.5M	+156K	+3.98%	$16.00	4.08M	Sep 17, 2021	See footnote	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	TYRA	Series A Preferred Stock	Conversion of derivative security	$0	-1.21M	-100%	$0.00^*	0	Sep 17, 2021	Common Stock	3.15M		See footnote	F1, F2
transaction	TYRA	Series B Preferred Stock	Conversion of derivative security	$0	-255K	-100%	$0.00^*	0	Sep 17, 2021	Common Stock	663K		See footnote	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Alta Partners NextGen Fund II Management, LLC is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may continue.

Explanation of Responses:

Id	Content
F1	On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.
F2	These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

Content

On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.