Christopher Moxham - Aug 10, 2021 Form 4 Insider Report for Fulcrum Therapeutics, Inc. (FULC)

Role: Chief Scientific Officer
Signature: /s/ Peter Thomson, as attorney-in-fact for Christopher Moxham
Stock symbol: FULC
Transactions as of: Aug 10, 2021
Transactions value $: -$505,422
Form type: 4
Date filed: 8/12/2021, 04:20 PM

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	FULC	Common Stock	Options Exercise	$162K	+20.7K		$7.84	20.7K	Aug 10, 2021	Direct	F1
transaction	FULC	Common Stock	Sale	-$352K	-20.7K	-100%	$17.00	0	Aug 10, 2021	Direct	F1
transaction	FULC	Common Stock	Options Exercise	$244K	+31.1K		$7.84	31.1K	Aug 10, 2021	Direct	F2
transaction	FULC	Common Stockm	Sale	-$559K	-31.1K	-100%	$18.00	0	Aug 10, 2021	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	FULC	Stock Option (right to buy)	Options Exercise	$0	-20.7K	-16.67%	$0.00	104K	Aug 10, 2021	Common Stock	20.7K	$7.84	Direct	F1, F3
transaction	FULC	Stock Option (right to buy)	Options Exercise	$0	-31.1K	-30%	$0.00	72.5K	Aug 10, 2021	Common Stock	31.1K	$7.84	Direct	F2, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 10, 2020.
F2	The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 28, 2021.
F3	The shares underlying the option are scheduled to vest 25% on the first anniversary of the vesting commencement date of January 22, 2020. The remainder of the shares underlying the grant shall vest in equal quarterly installments over the following three years until the fourth anniversary of the vesting commencement date, subject to continued service.