Lucille S. Salhany - 10 Nov 2025 Form 4 Insider Report for 22nd Century Group, Inc. (XXII)

Role: Director
Signature: /s/ Lucille S. Salhany by John Wolfel, as Attorney-in-fact
Issuer symbol: XXII
Transactions as of: 10 Nov 2025
Net transactions value: $0
Form type: 4
Filing time: 13 Nov 2025, 17:34:39 UTC
Previous filing: 12 Mar 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
SALHANY LUCILLE S	Director	C/O 22ND CENTURY GROUP, INC., 321 FARMINGTON RD., MOCKSVILLE	/s/ Lucille S. Salhany by John Wolfel, as Attorney-in-fact	13 Nov 2025	0001231076

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	XXII	Common Stock	Award	$0	+11,006	+10191%	$0.000000	11,114	10 Nov 2025	Direct	F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	XXII	Non-Qualified Stock Option	Award	$0	+33,020		$0.000000	33,020	10 Nov 2025	Common Stock	33,020	$1.27	Direct	F3
holding	XXII	Non-Qualified Stock Option						322	10 Nov 2025	Common Stock	322	$46.23	Direct	F2, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The restricted stock units vest 1/3 per year on November 10, 2026, 2027 and 2028, subject to continued service with the Company.
F2	The amount shown reflects the number of shares held following the reported transaction, as adjusted for a 1-for-23 stock split effectuated by the issuer on June 20, 2025.
F3	Options vest 1/3 per year on the anniversary of the date of grant, subject to continued service with the Company.