Duncan McKechnie - 24 Feb 2026 Form 4 Insider Report for VERTEX PHARMACEUTICALS INC / MA (VRTX)

Signature
/s/ Christiana Stevenson, Attorney-in-Fact
Issuer symbol
VRTX
Transactions as of
24 Feb 2026
Net transactions value
-$2,817,866
Form type
4
Filing time
26 Feb 2026, 18:48:22 UTC
Previous filing
19 Feb 2026
Next filing
06 Mar 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
McKechnie Duncan EVP, Chief Commercial Officer C/O VERTEX PHARMACEUTICALS INCORPORATED, 50 NORTHERN AVENUE, BOSTON /s/ Christiana Stevenson, Attorney-in-Fact 26 Feb 2026 0002062139

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction VRTX Common Stock Tax liability $423,501 -873 -3.7% $485.11 22,469 24 Feb 2026 Direct
transaction VRTX Common Stock Sale $1,215,875 -2,500 -11% $486.35 19,969 25 Feb 2026 Direct F1
transaction VRTX Common Stock Sale $1,178,490 -2,410 -12% $489.00 17,559 25 Feb 2026 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Transaction made pursuant to Mr. McKechnie's company approved trading plan under Rule 10b5-1, which was entered into on 11/25/2025.