| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Lagarde Michel | Director | C/O VERTEX PHARMACEUTICALS INCORPORATED, 50 NORTHERN AVE, BOSTON | /s/ Christiana Stevenson, Attorney-in-Fact | 05 May 2025 | 0001518973 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRTX | Stock Option (Right to Buy) | Award | $0 | +2,398 | $0.000000 | 2,398 | 01 May 2025 | Common Stock | 2,398 | $502.97 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Fully vested. |