| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Grygiel Nancy A. | SVP & CCO | ONE AMGEN CENTER DRIVE, THOUSAND OAKS | /s/ Nancy A. Grygiel | 20 Nov 2025 | 0001816414 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | AMGN | Common Stock | Options Exercise | $266,190 | +1,500 | +21% | $177.46 | 8,725 | 20 Nov 2025 | Direct | |
| transaction | AMGN | Common Stock | Sale | $505,894 | -1,500 | -17% | $337.26 | 7,225 | 20 Nov 2025 | Direct | F1 |
| transaction | AMGN | Common Stock | Options Exercise | $266,501 | +1,639 | +23% | $162.60 | 8,864 | 20 Nov 2025 | Direct | |
| transaction | AMGN | Common Stock | Sale | $552,773 | -1,639 | -18% | $337.26 | 7,225 | 20 Nov 2025 | Direct | F1, F2 |
| holding | AMGN | Common Stock | 105 | 20 Nov 2025 | 401(k) Plan | F3 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | AMGN | Nqso (Right to Buy) | Options Exercise | $0 | -1,500 | -43% | $0.000000 | 1,970 | 20 Nov 2025 | Common Stock | 1,500 | $177.46 | Direct | |
| transaction | AMGN | Nqso (Right to Buy) | Options Exercise | $0 | -1,639 | -100% | $0.000000 | 0 | 20 Nov 2025 | Common Stock | 1,639 | $162.60 | Direct |
| Id | Content |
|---|---|
| F1 | The price reported is an average price. The prices ranged from $337.17 to $337.69 per share. Full information regarding the number of shares purchased at each separate price within the range is available upon request by the SEC staff, the issuer or a security holder of the issuer. |
| F2 | These shares include 96 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. Second Amended and Restated 2009 Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited to the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount. |
| F3 | These are shares acquired under the Company's 401(k) Plan and represent interests in the Company's stock fund as of this filing. |