(DHR)

Role: EVP & Chief Financial Officer
Signature: /s/ James F. O'Reilly, attorney-in-fact for Matthew McGrew
Issuer symbol: DHR
Transactions as of: 11 Nov 2025
Net transactions value: -$2,454,421
Form type: 4
Filing time: 13 Nov 2025, 17:00:35 UTC
Previous filing: 04 Mar 2025
Next filing: 04 Feb 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
McGrew Matthew	EVP & Chief Financial Officer	2200 PENNSYLVANIA AVENUE, NW, SUITE 800W, WASHINGTON	/s/ James F. O'Reilly, attorney-in-fact for Matthew McGrew	13 Nov 2025	0001754423

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	DHR	Common Stock	Options Exercise	$1,016,410	+16,172	+81%	$62.85	36,234	11 Nov 2025	Direct
transaction	DHR	Common Stock	Sale	$3,470,831	-16,172	-45%	$214.62	20,062	11 Nov 2025	Direct	F1
holding	DHR	Common Stock						10,222	11 Nov 2025	By 401(k)

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	DHR	Employee stock option (right to buy)	Options Exercise	$0	-16,172	-100%	$0.000000	0	11 Nov 2025	Common Stock	16,172	$62.85	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $214.580 to $214.810, inclusive. The reporting person undertakes to provide to Danaher Corporation, any securityholder of Danaher Corporation, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.
F2	One third of the options granted became exercisable on each of the third, fourth and fifth anniversaries of the grant date, which was November 15, 2015.

Content

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $214.580 to $214.810, inclusive. The reporting person undertakes to provide to Danaher Corporation, any securityholder of Danaher Corporation, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

One third of the options granted became exercisable on each of the third, fourth and fifth anniversaries of the grant date, which was November 15, 2015.