Bain Capital Life Sciences Investors, LLC

Q4 2025 13F Holdings Report, Stock Holdings

Signature - Title
Adam Koppel - Partner of Bain Capital Life Sciences Investors, LLC
Location
Boston, MA
Holdings as of
31 Dec 2025
Value $
$1,305,660,830
Num holdings
19
Filing time
17 Feb 2026, 16:30:04 UTC
Form type
13F-HR
Description
All US holdings of this investor are reported in this report. Top holdings included HTFL, NAMS, OLMA, SVRA, and PHVS.
Previous filing
Q3 2025 - 14 Nov 2025
Sym Weight Trade Impact Company Class Share Change Activity Value Change $ Value $ * Price $ Shares Principal
Filing 2025 Q4 compared to 2025 Q3 by default. Changes are calculated vs the previous SEC filing.
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.

Person Signing this Report on Behalf of Reporting Manager:

Name Title City, State Date
Adam Koppel Partner of Bain Capital Life Sciences Investors, LLC Boston, Massachusetts 17 Feb 2026

Bain Capital Life Sciences Investors, LLC ("BCLSI") is (i) the manager of Bain Capital Life Sciences Investors II, LLC, which is the general partner of Bain Capital Life Sciences Fund II, L.P., which is the manager of BCLS II Investco (GP), LLC, which is the general partner of BCLS II Investco, LP, (ii) the manager of Bain Capital Life Sciences III General Partner, LLC, which is the general partner of Bain Capital Life Sciences Fund III, L.P., which is the (a) sole member of Bain Capital Life Sciences Opportunities III GP, LLC, which is the general partner of Bain Capital Life Sciences Opportunities III, LP and (b) the managing member of BCLS Fund III Investments GP, LLC, which is the general partner of BCLS Fund III Investments, LP. and (iii) the manager of Bain Capital Life Sciences IV General Partner, LLC, which is the general partner of Bain Capital Life Sciences Fund IV, L.P., which is the sole member of Bain Capital Life Sciences Opportunities IV GP, LLC, which is the general partner of Bain Capital Life Sciences Opportunities IV, L.P. The information included on the Information Table with respect to the holdings of Annexon Inc. ("ANNX"), C4 Therapeutics, Inc. ("CCCC"), Cabaletta Bio, Inc. ("CABA"), NewAmsterdam Pharma Company NV ("NAMS"), Olema Pharmaceuticals, Inc. ("OLMA"), Savara Inc. ("SVRA"), Solid Biosciences Inc. ("SLDB"), X4 Pharmaceuticals, Inc. ("XFOR") and Xilio Therapeutics, Inc. ("XLO") reflect the exercise or conversion of warrants or other convertible securities held by affiliates of BCLSI after giving effect to provisions that prevent the exercise of such securities if the beneficial ownership of such persons would exceed 9.99% of the underlying security following such exercise. As of December 31, 2025, affiliates of BCLSI held an aggregate of 4,474,126 shares of ANNX common stock, 3,131,910 shares of CCCC common stock, 4,260,888 shares of CABA common stock, 5,673,913 ordinary shares of NAMS, 1,989,775 shares of OLMA common stock, 14,789,777 shares of SVRA common stock, 4,505,922 shares of SLDB common stock, 615,649 shares of XFOR common stock and 1,112,944 shares of XLO common stock.

Other Included Managers (14):

Num Name Location File Number
1 Bain Capital Life Sciences Investors II, LLC Boston, MA 028-20816
2 Bain Capital Life Sciences Fund II, L.P. Boston, MA 028-20814
3 BCLS II Investco (GP), LLC Boston, MA 028-22976
4 BCLS II Investco, LP Boston, MA 028-22978
5 Bain Capital Life Sciences III General Partner, LLC Boston, MA 028-22975
6 Bain Capital Life Sciences Fund III, L.P. Boston, MA 028-22979
7 Bain Capital Life Sciences Opportunities III GP, LLC Boston, MA 028-22968
8 Bain Capital Life Sciences Opportunities III, LP Boston, MA 028-22966
9 BCLS Fund III Investments GP, LLC Boston, MA 028-25138
10 BCLS Fund III Investments, LP Boston, MA 028-25140
11 Bain Capital Life Sciences IV General Partner, LLC Boston, MA
12 Bain Capital Life Sciences Fund IV, L.P. Boston, MA
13 Bain Capital Life Sciences Opportunities IV GP, LLC Boston, MA
14 Bain Capital Life Sciences Opportunities IV, L.P. Boston, MA