Sofinnova Investments, Inc.

Q4 2025 13F Holdings Report, Stock Holdings

Signature - Title
Nathalie Auber - Attorney-in-Fact
Location
Menlo Park, CA
Holdings as of
31 Dec 2025
Value $
$2,319,284,145
Num holdings
60
Filing time
13 Feb 2026, 15:26:56 UTC
Form type
13F-HR
Description
All US holdings of this investor are reported in this report. Top holdings included NTRA, JAZZ, AZN, VERA, and BMY.
Previous filing
Q3 2025 - 14 Nov 2025
Options Holdings
Showing stock holdings, see here for options holdings
Sym Weight Trade Impact Company Class Share Change Activity Value Change $ Value $ * Price $ Shares Principal
Filing 2025 Q4 compared to 2025 Q3 by default. Changes are calculated vs the previous SEC filing.
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.

Person Signing this Report on Behalf of Reporting Manager:

Name Title City, State Date
Nathalie Auber Attorney-in-Fact Menlo Park, California 13 Feb 2026

*Sofinnova Investments, Inc. is filing this Form 13F on behalf of itself and the general partner entities of the investment funds for which it serves as the investment adviser, Sofinnova Management VIII, L.L.C., Sofinnova Management IX, L.L.C., Sofinnova Management X, L.L.C., Sofinnova BioEquities GP LLC, and Sofinnova Synergy GP LLC.