13F History

VR Adviser, LLC

Q4 2022 13F Holdings Report, Restatement, Stock Holdings

Signature - Title: Sherman G. Souther - Authorized Signatory
Location: New York, NY
Holdings as of: December 31, 2022
Value $: $594M
Num holdings: 28
Date filed: 5/15/2023, 04:16 PM
Description: All US holdings of this investor are reported in this report. The Form 13F report requires disclosure of the manager that files the report, the name and class of the security, the CUSIP code, the number of shares as of the end of the calendar quarter for which the report is filed, and the total market value. The market value column should not be used as a substitute for Assets Under Management (AUM), as it does not include cash held in accounts.
Previous filing: Q3 2022 - May 15, 2023
Next filing: Q1 2023 - May 15, 2023

Sym	Weight	Trade Impact	Company	Class	Shares Change	Activity	Value Change $	Value $	* Price $	Shares	Principal

Filing 2022 Q4 - Restatement compared to 2022 Q3 - Restatement by default.

Compare Q4 2022 to

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.

Person Signing this Report on Behalf of Reporting Manager:

Name	Title	City, State	Date
Sherman G. Souther	Authorized Signatory	Palo Alto, California	5/15/2023

Note: VR Adviser, LLC is filing this Form 13F on behalf of itself and the general partner entities of the investment funds for which it serves as the investment adviser, VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC and Venrock Opportunities Management, LLC. Note: This amendment is being filed solely to remove holdings of securities of DBV Technologies S A ("DBV") from the reporting manager's holdings of 13(f) securities as of December 31, 2022. The reporting manager's holdings of DBV equity securities as of December 31, 2022 consisted of ordinary shares, which are not considered "Section 13(f) securities" and are, therefore, not reportable on Form 13F, in contrast to American depositary shares, which are reportable on Form 13F. This amendment does not reflect the disposition of any securities of DBV by the reporting manager, but merely reflects the fact that the holdings as of December 31, 2022 were in the form of ordinary shares. As of December 31, 2022, the reporting manager's holdings included 9,300,000 ordinary shares of DBV.