13F Filings History of TCG Crossover Management, LLC

Latest 13F report
Q4 2025 - 17 Feb 2026
Value $
$3,021,699,270
Signature - Title
Craig Skaling - CCO & CFO
Location
Palo Alto, CA
Summary
This page shows a list of all the recent 13F filings made by TCG Crossover Management, LLC. Form 13F is required to be filed within 45 days of the end of a calendar quarter. TCG Crossover Management, LLC reported 43 stock holdings with total value $3,021,699,270 as of Q4 2025. Top holdings included ABVX, COGT, CGON, TNGX, and CNTA.

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Holdings Value
Quarter Holdings Value $ Bought Sold Net Top Holdings Form Type Filing Time
Q4 2025 43 $3,021,699,270 +$430,697,875 -$218,953,097 +$211,744,778 ABVX, COGT, CGON, TNGX, CNTA 13F-HR 17 Feb 2026, 11:05
Q3 2025 40 $2,032,902,053 +$342,325,248 -$139,151,827 +$203,173,421 ABVX, CGON, COGT, AMLX, CNTA 13F-HR 14 Nov 2025, 17:49
Q2 2025 37 $875,508,102 +$64,421,814 -$89,187,741 -$24,765,927 CGON, TNGX, COGT, OCUL, CDTX 13F-HR 14 Aug 2025, 17:29
Q1 2025 37 $733,085,569 +$13,055,700 -$29,487,411 -$16,431,711 CGON, COGT, CNTA, MLYS, OCUL 13F-HR 14 May 2025, 12:50
Q4 2024 38 $1,023,348,505 +$179,223,250 -$71,886,967 +$107,336,283 CGON, DYN, XNCR, COGT, CNTA 13F-HR 14 Feb 2025, 16:30
Q3 2024 36 $1,180,307,005 +$203,175,188 -$121,605,905 +$81,569,283 CGON, DYN, COGT, ABVX, EWTX 13F-HR 14 Nov 2024, 12:46
Q2 2024 32 $959,501,740 +$122,237,980 -$198,393,270 -$76,155,290 CGON, DYN, ABVX, SLN, COGT 13F-HR 14 Aug 2024, 11:23
Q1 2024 33 $1,264,901,605 +$548,004,607 -$269,814,152 +$278,190,455 CGON, DYN, ATXS, SLN, GPCR 13F-HR 15 May 2024, 09:10
Q4 2023 29 $901,701,904 +$99,687,906 -$34,439,909 +$65,247,997 GPCR, INBX, ICVX, ANTX, RYZB 13F-HR 14 Feb 2024, 10:19
Q3 2023 26 $679,112,367 +$279,992,557 -$170,102,464 +$109,890,093 GPCR, COGT, GERN, ANTX, SVRA 13F-HR 14 Nov 2023, 10:12
Q2 2023 22 $609,793,658 +$109,394,936 -$149,377,688 -$39,982,752 ISEE, GERN, COGT, VECT, AVTE 13F-HR 14 Aug 2023, 12:58
Q1 2023 22 $513,028,149 +$44,450,660 -$85,372,287 -$40,921,627 ISEE, COGT, GERN, MDGL, TYRA 13F-HR 15 May 2023, 13:50
Q4 2022 21 $566,607,730 +$212,199,601 -$35,219,301 +$176,980,300 ISEE, MDGL, COGT, CBAY, GERN 13F-HR 14 Feb 2023, 10:11
Q3 2022 21 $333,401,000 +$54,484,323 -$32,428,318 +$22,056,005 ISEE, COGT, GERN, VRDN, SLN 13F-HR 14 Nov 2022, 13:04
Q2 2022 22 $235,414,000 +$30,607,971 -$6,276,442 +$24,331,529 COGT, ISEE, GERN, KURA, CBAY 13F-HR 15 Aug 2022, 14:52
Q1 2022 20 $249,097,000 +$60,636,666 -$1,504,326 +$59,132,340 ISEE, VRDN, COGT, ACRS, GERN 13F-HR 16 May 2022, 16:01
Q4 2021 15 $213,563,000 $0 $0 $0 ISEE, VRDN, COGT, CBAY, ALPN 13F-HR 17 Feb 2022, 18:57