SPHERA FUNDS MANAGEMENT LTD.

Holdings History for TWILIO INC - CLASS A COMMON STOCK (TWLO)

Symbol: TWLO on NYSE
Investment type: Equity / CLASS A COMMON STOCK

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2021		-1.1%	$0	0	-35,500	-100%	$110.41	Q4 2021
30 Sep 2021	1.1%	+0.28%	$11,326,000	35,500	+9,000	+34%	$319.04	Q3 2021
30 Jun 2021	0.99%	+0.99%	$10,445,000	26,500	+26,500	NEW	$394.15	Q2 2021

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.