FRANKLIN STREET ADVISORS INC /NC

Holdings History for ProQR Therapeutics N.V. - Ordinary Shares, nominal value Euro 0.04 per share (PRQR)

Symbol: PRQR on Nasdaq
Investment type: Equity / Ordinary Shares, nominal value Euro 0.04 per share

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025	0.02%	0%	$303,000	150,000	0		$2.02	Q4 2025
30 Sep 2025	0.02%	0%	$319,500	150,000	0		$2.13	Q3 2025
30 Jun 2025	0.02%	0%	$306,000	150,000	0		$2.04	Q2 2025
31 Mar 2025	0.01%	0%	$200,000	150,000	0		$1.33	Q1 2025
31 Dec 2024	0.03%	0%	$398,000	150,000	0		$2.65	Q4 2024
30 Sep 2024	0.02%	0%	$273,000	150,000	0		$1.82	Q3 2024
30 Jun 2024	0.02%	0%	$249,000	150,000	0		$1.66	Q2 2024
31 Mar 2024	0.03%	0%	$343,000	150,000	0		$2.29	Q1 2024
31 Dec 2023	0.02%	0%	$297,000	150,000	0		$1.98	Q4 2023
30 Sep 2023	0.02%	0%	$195,000	150,000	0		$1.30	Q3 2023
30 Jun 2023	0.02%	0%	$243,000	150,000	0		$1.62	Q2 2023
31 Mar 2023	0.03%	0%	$320,000	150,000	0		$2.13	Q1 2023
31 Dec 2022	0.05%	0%	$555,000	150,000	0		$3.70	Q4 2022
30 Sep 2022	0.01%	0%	$112,000	150,000	0		$0.75	Q3 2022
30 Jun 2022	0.01%	+0%	$117,000	150,000	+50,000	+50%	$0.78	Q2 2022
31 Mar 2022	0.01%	-0%	$91,000	100,000	-10,000	-9.1%	$0.91	Q1 2022
31 Dec 2021	0.07%	+0.01%	$881,000	110,000	+10,000	+10%	$8.01	Q4 2021
30 Sep 2021	0.07%	0%	$837,000	100,000	0		$8.37	Q3 2021
30 Jun 2021	0.06%	0%	$674,000	100,000	0		$6.74	Q2 2021
31 Mar 2021	0.06%	+0.02%	$661,000	100,000	+40,000	+67%	$6.61	Q1 2021
31 Dec 2020	0.02%	0%	$252,000	60,000	0		$4.20	Q4 2020
30 Sep 2020	0.03%	0%	$287,000	60,000	0		$4.78	Q3 2020
30 Jun 2020	0.04%	0%	$365,000	60,000	0		$6.08	Q2 2020
31 Mar 2020	0.05%	0%	$329,000	60,000	0		$5.48	Q1 2020
31 Dec 2019	0.07%	0%	$595,000	60,000	0		$9.92	Q4 2019
30 Sep 2019	0.04%	0%	$346,000	60,000	0		$5.77	Q3 2019
30 Jun 2019	0.07%	0%	$546,000	60,000	0		$9.10	Q2 2019
31 Mar 2019	0.12%	0%	$832,000	60,000	0		$13.87	Q1 2019
31 Dec 2018	0.15%	0%	$947,000	60,000	0		$15.78	Q4 2018
30 Sep 2018	0.16%	-0.08%	$1,161,000	60,000	-30,000	-33%	$19.35	Q3 2018
30 Jun 2018	0.1%	+0.03%	$657,000	90,000	+30,000	+50%	$7.30	Q2 2018
31 Mar 2018	0.03%	+0.03%	$185,000	60,000	+60,000	NEW	$3.08	Q1 2018

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.