What does CUSIP 92532F100 represent in this 13F holders report?

CUSIP 92532F100 is the security identifier for VRTX - VERTEX PHARMACEUTICALS INC / MA - Common Stock used to aggregate holder disclosures.

How many institutions held VRTX - VERTEX PHARMACEUTICALS INC / MA - Common Stock in Q4 2021?

1015 institutional investors reported VRTX - VERTEX PHARMACEUTICALS INC / MA - Common Stock for Q4 2021. Use the holders table for investor-level position and value details.

VERTEX PHARMACEUTICALS INC / MA - Common Stock (VRTX)

CUSIP: 92532F100

Q4 2021 13F Holders as of 31 Dec 2021

Type / Class: Equity / Common Stock
Shares outstanding: 254,691,824
Total 13F shares: 229,577,277
Share change: -1,553,655
Total reported value: $50,395,687,889
Put/Call ratio: 77%
Price per share: $219.60
Number of holders: 1,015
Value change: -$237,458,680
Number of buys: 463
Number of sells: 447

Quarterly Holders Quick Answers

What is CUSIP 92532F100?
CUSIP 92532F100 identifies VRTX - VERTEX PHARMACEUTICALS INC / MA - Common Stock in SEC institutional holdings data.

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Back to full security ownership history for the broader multi-quarter picture.
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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2022
Previous quarter: Q3 2021

Recent filing periods for CUSIP 92532F100:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of VRTX - VERTEX PHARMACEUTICALS INC / MA - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
BlackRock Finance, Inc.	13F	Company	9.2%	23,547,895	$4,271,352,000	—	30 Sep 2021	13F
VANGUARD GROUP INC	13F	Company	8%	20,442,691	$3,708,101,000	—	30 Sep 2021	13F
STATE STREET CORP	13F	Company	4.8%	12,323,416	$2,235,344,000	—	30 Sep 2021	13F
Capital World Investors	13F	Company	4.3%	11,042,302	$2,002,970,000	—	30 Sep 2021	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	3.6%	9,068,848	$1,644,998,000	—	30 Sep 2021	13F
LOOMIS SAYLES & CO L P	13F	Company	2.8%	7,005,992	$1,270,817,000	—	30 Sep 2021	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	2.4%	6,091,089	$1,104,862,000	—	30 Sep 2021	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	2.2%	5,698,247	$1,033,605,000	—	30 Sep 2021	13F
Clearbridge Investments, LLC	13F	Company	2%	5,112,404	$927,339,000	—	30 Sep 2021	13F
FMR LLC	13F	Company	1.9%	4,877,098	$884,657,000	—	30 Sep 2021	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	1.7%	4,302,352	$778,281,000	—	30 Sep 2021	13F
JPMORGAN CHASE & CO	13F	Company	1.7%	4,211,732	$763,967,000	—	30 Sep 2021	13F
Capital International Investors	13F	Company	1.6%	3,949,552	$716,412,000	—	30 Sep 2021	13F
AMERIPRISE FINANCIAL INC	13F	Company	1.3%	3,389,090	$614,704,000	—	30 Sep 2021	13F
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	13F	Company	1.2%	3,149,240	$571,241,000	—	30 Sep 2021	13F
BANK OF AMERICA CORP /DE/	13F	Company	1.2%	3,030,356	$549,677,000	—	30 Sep 2021	13F
NORTHERN TRUST CORP	13F	Company	1.2%	2,994,490	$543,171,000	—	30 Sep 2021	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	1.1%	2,758,853	$500,428,348	—	30 Sep 2021	13F
DEUTSCHE BANK AG\	13F	Company	1.1%	2,686,591	$487,320,000	—	30 Sep 2021	13F
NORGES BANK	13F	Company	0.99%	2,526,180	$458,224,000	—	30 Sep 2021	13F
JANUS HENDERSON GROUP PLC	13F	Company	0.84%	2,134,778	$387,231,000	—	30 Sep 2021	13F
Bank of New York Mellon Corp	13F	Company	0.82%	2,088,787	$378,884,000	—	30 Sep 2021	13F
Legal & General Group Plc	13F	Company	0.81%	2,068,334	$375,176,000	—	30 Sep 2021	13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	13F	Company	0.79%	2,006,318	$363,926,000	—	30 Sep 2021	13F
HARDING LOEVNER LP	13F	Company	0.75%	1,911,103	$346,655,000	—	30 Sep 2021	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	0.74%	1,891,486	$343,097,000	—	30 Sep 2021	13F
Bellevue Group AG	13F	Company	0.69%	1,761,616	$319,540,000	—	30 Sep 2021	13F
D. E. Shaw & Co., Inc.	13F	Company	0.67%	1,714,634	$311,017,000	—	30 Sep 2021	13F
ARK Investment Management LLC	13F	Company	0.67%	1,709,751	$310,132,000	—	30 Sep 2021	13F
CANADA PENSION PLAN INVESTMENT BOARD	13F	Company	0.66%	1,692,794	$307,056,000	—	30 Sep 2021	13F
CAISSE DE DEPOT ET PLACEMENT DU QUEBEC	13F	Company	0.59%	1,495,216	$271,217,000	—	30 Sep 2021	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.55%	1,393,762	$252,815,000	—	30 Sep 2021	13F
Nuveen Asset Management, LLC	13F	Company	0.54%	1,365,225	$247,638,000	—	30 Sep 2021	13F
MACQUARIE GROUP LTD	13F	Company	0.53%	1,350,515	$244,970,000	—	30 Sep 2021	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.49%	1,241,985	$225,285,000	—	30 Sep 2021	13F
Invesco Ltd.	13F	Company	0.48%	1,214,493	$220,294,000	—	30 Sep 2021	13F
Man Group plc	13F	Company	0.48%	1,211,443	$219,744,000	—	30 Sep 2021	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.44%	1,131,591	$205,259,000	—	30 Sep 2021	13F
Sumitomo Mitsui Trust Group, Inc.	13F	Company	0.43%	1,092,041	$198,085,000	—	30 Sep 2021	13F
Impax Asset Management Group plc	13F	Company	0.42%	1,074,736	$194,946,000	—	30 Sep 2021	13F
PICTET ASSET MANAGEMENT SA	13F	Company	0.42%	1,064,822	$193,148,000	—	30 Sep 2021	13F
APG Asset Management N.V.	13F	Company	0.48%	1,228,689	$192,305,000	—	30 Sep 2021	13F
BANK OF MONTREAL /CAN/	13F	Company	0.41%	1,053,359	$192,016,000	—	30 Sep 2021	13F
MORGAN STANLEY	13F	Company	0.41%	1,042,513	$189,100,000	—	30 Sep 2021	13F
Swiss National Bank	13F	Company	0.4%	1,023,675	$185,684,000	—	30 Sep 2021	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.38%	959,684	$174,077,000	—	30 Sep 2021	13F
Avidity Partners Management LP	13F	Company	0.36%	926,400	$168,040,000	—	30 Sep 2021	13F
ORBIMED ADVISORS LLC	13F	Company	0.34%	877,400	$159,152,000	—	30 Sep 2021	13F
Manning & Napier Group, LLC	13F	Company	0.34%	872,928	$158,339,000	—	30 Sep 2021	13F
FRANKLIN RESOURCES INC	13F	Company	0.34%	866,924	$157,250,000	—	30 Sep 2021	13F

Institutional Holders of VERTEX PHARMACEUTICALS INC / MA - Common Stock (VRTX) as of Q4 2021

As of 31 Dec 2021, VERTEX PHARMACEUTICALS INC / MA - Common Stock (VRTX) was held by 1,015 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 229,577,277 shares. The largest 10 holders included BlackRock Inc., VANGUARD GROUP INC, STATE STREET CORP, Capital World Investors, ALLIANCEBERNSTEIN L.P., FMR LLC, LOOMIS SAYLES & CO L P, WELLINGTON MANAGEMENT GROUP LLP, PRICE T ROWE ASSOCIATES INC /MD/, and Clearbridge Investments, LLC. This page lists 1,017 institutional shareholders reporting positions in this security for the Q4 2021 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

920

Q4 2021 holders

1,015

Holder diff

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 Value $	Q4 2021 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.