Ventyx Biosciences, Inc. - Common Stock, $0.0001 par value per share (VTYX) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2021 to Q4 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
VTYX on Nasdaq
Shares outstanding
71,364,430
Price per share
$13.89
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
52,225,020
Total reported value
$471,585,552
% of total 13F portfolios
0%
Share change
+7,037,465
Value change
+$103,494,344
Number of holders
138
Price from insider filings
$13.89
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Ventyx Biosciences, Inc. - Common Stock, $0.0001 par value per share (VTYX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Affinity Asset Advisors, LLC 9% +55% $58,381,906 +$21,744,625 6,465,041 +59% Affinity Asset Advisors, LLC 22 Jan 2026
NSV Investments I, L.P. 7.6% $6,836,036 5,425,425 Somasundaram Subramaniam 10 Mar 2025
GLAZER CAPITAL, LLC 6.2% $61,754,996 4,446,004 Glazer Capital, LLC 12 Feb 2026
Mohan Raju 6% 0% $39,622,524 +$48,060 4,387,682 +0.12% Raju Mohan 07 Jan 2026
Subramaniam Somu 5.8% $37,232,113 4,122,975 Subramaniam Somu 07 Jan 2026
NSV Partners III LP 5.7% $5,153,368 4,089,975 Subramaniam Somu 28 Mar 2025
VANGUARD GROUP INC 5.3% $11,725,822 3,769,997 The Vanguard Group 30 Sep 2025
Point72 Asset Management, L.P. 4.5% -48% $9,981,996 -$8,351,669 3,209,645 -46% Point72 Asset Management, L.P. 30 Sep 2025
Sio Capital Management, LLC 3.6% -35% $3,254,145 -$1,844,819 2,582,655 -36% Sio Capital Management, LLC 31 Mar 2025
CITADEL ADVISORS LLC 2% $1,776,097 1,409,601 Kenneth Griffin 31 Mar 2025
BlackRock, Inc. 1.9% $2,891,112 1,350,987 BlackRock, Inc. 30 Jun 2025
BANK OF AMERICA CORP /DE/ 1.4% -73% $1,280,978 -$4,535,858 1,016,649 -78% BANK OF AMERICA CORP /DE/ 31 Mar 2025
Flynn James E 0.76% $673,769 534,737 Deerfield Mgmt, L.P. 31 Dec 2024
MORGAN STANLEY 0.3% -95% $2,143,343 -$36,594,590 237,358 -94% Morgan Stanley 31 Jan 2026

As of 31 Dec 2025, 138 institutional investors reported holding 52,225,020 shares of Ventyx Biosciences, Inc. - Common Stock, $0.0001 par value per share (VTYX). This represents 73% of the company’s total 71,364,430 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Ventyx Biosciences, Inc. - Common Stock, $0.0001 par value per share (VTYX) together control 60% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Affinity Asset Advisors, LLC 9.1% 6,484,558 +65% 4.2% $58,555,559
MORGAN STANLEY 6% 4,292,951 +1661% 0% $38,765,348
VANGUARD GROUP INC 5.5% 3,943,566 +4.6% 0% $35,610,400
BlackRock, Inc. 4.4% 3,142,440 +166% 0% $28,376,233
TANG CAPITAL MANAGEMENT LLC 3.9% 2,814,000 -9.2% 1.3% $25,410,420
BAKER BROS. ADVISORS LP 3.3% 2,349,280 +130% 0.12% $21,213,998
BRAIDWELL LP 2.7% 1,920,255 0.55% $17,339,903
D. E. Shaw & Co., Inc. 2.3% 1,665,474 +219% 0.01% $15,039,230
MPM BIOIMPACT LLC 2.3% 1,639,061 1.7% $14,800,721
CITADEL ADVISORS LLC 2.2% 1,563,611 -17% 0.01% $14,119,407
Connor, Clark & Lunn Investment Management Ltd. 1.7% 1,203,997 +14% 0.03% $10,872,093
SUSQUEHANNA INTERNATIONAL GROUP, LLP 1.6% 1,118,275 +64% 0.01% $10,098,023
Point72 Asset Management, L.P. 1.5% 1,056,520 -67% 0.01% $9,540,376
683 Capital Management, LLC 1.5% 1,040,000 +4% 0.78% $9,391,200
MILLENNIUM MANAGEMENT LLC 1.4% 989,917 -40% 0.01% $8,938,951
Ikarian Capital, LLC 1.3% 958,704 -27% 1.1% $8,657,097
JANE STREET GROUP, LLC 1.3% 941,067 +144% 0.01% $8,497,835
GOLDMAN SACHS GROUP INC 1.2% 837,602 +106% 0% $7,563,546
ACADIAN ASSET MANAGEMENT LLC 1.1% 773,512 +9.9% 0.01% $6,978,000
DIMENSIONAL FUND ADVISORS LP 1% 742,544 +76% 0% $6,702,415
Balyasny Asset Management L.P. 1% 735,711 0.01% $6,643,470
GEODE CAPITAL MANAGEMENT, LLC 1% 722,355 -0.87% 0% $6,526,279
Artia Global Partners LP 0.98% 695,982 1% $6,284,717
TUDOR INVESTMENT CORP ET AL 0.82% 583,611 0.03% $5,270,007
STATE STREET CORP 0.77% 548,743 +91% 0% $4,955,149

Institutional Holders of Ventyx Biosciences, Inc. - Common Stock, $0.0001 par value per share (VTYX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 52,225,020 $471,585,552 +$103,494,344 $9.03 138
2025 Q3 43,853,431 $136,378,109 -$468,450 $3.11 109
2025 Q2 44,427,101 $95,066,026 +$2,059,789 $2.14 112
2025 Q1 44,413,797 $51,071,272 -$13,704,510 $1.15 116
2024 Q4 54,449,340 $119,241,531 +$4,099,056 $2.19 122
2024 Q3 52,481,458 $114,411,828 -$11,847,686 $2.18 115
2024 Q2 57,252,817 $132,254,360 -$36,320,827 $2.31 114
2024 Q1 58,990,812 $323,851,608 +$111,976,682 $5.50 122
2023 Q4 43,247,569 $106,821,389 -$553,553,365 $2.47 118
2023 Q3 54,583,406 $1,895,690,669 +$62,410,449 $34.73 137
2023 Q2 52,627,413 $1,726,219,124 +$92,758,720 $32.80 146
2023 Q1 49,748,691 $1,666,552,448 +$243,592,644 $33.50 143
2022 Q4 42,351,969 $1,388,715,670 +$101,470,239 $32.79 122
2022 Q3 39,299,041 $1,371,090,008 +$167,335,144 $34.91 104
2022 Q2 34,630,744 $423,528,800 +$16,981,526 $12.23 58
2022 Q1 33,233,009 $448,438,000 +$21,644,387 $13.57 53
2021 Q4 30,695,789 $601,183,000 +$601,183,000 $19.86 45