| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JENNISON ASSOCIATES LLC | 8.9% | +24% | $29,447,817 | +$5,797,046 | 12,584,537 | +25% | Jennison Associates LLC | 30 Sep 2025 |
| PRUDENTIAL FINANCIAL INC | 8.9% | +21% | $29,447,817 | +$5,132,486 | 12,584,537 | +21% | PRUDENTIAL FINANCIAL INC | 30 Sep 2025 |
| T. Rowe Price Investment Management, Inc. | 11% | +24% | $24,243,163 | +$4,674,939 | 10,360,326 | +24% | T. Rowe Price Investment Management, Inc. | 31 Oct 2025 |
| Bain Capital Life Sciences Opportunities III, LP | 10% | $15,483,400 | 9,677,125 | Bain Capital Life Sciences Opportunities III, LP | 30 Jun 2025 | |||
| Cormorant Asset Management, LP | 10% | +90% | $22,445,240 | +$10,745,240 | 9,591,983 | +92% | Cormorant Asset Management, LP | 30 Sep 2025 |
| Adage Capital Management, L.P. | 10% | $14,404,128 | 9,002,580 | Adage Capital Management, L.P. | 30 Jun 2025 | |||
| Alyeska Investment Group, L.P. | 6% | -39% | $13,572,000 | -$7,264,219 | 5,800,000 | -35% | Alyeska Investment Group, L.P. | 30 Sep 2025 |
| VANGUARD GROUP INC | 3.8% | $5,245,105 | 3,450,727 | The Vanguard Group | 30 Jun 2025 | |||
| CITADEL ADVISORS LLC | 3.4% | -36% | $7,371,644 | -$3,903,787 | 3,150,275 | -35% | Kenneth Griffin | 30 Sep 2025 |
| Nichtberger Steven | 3.3% | $4,855,198 | 3,034,499 | Nichtberger Steven | 30 Jun 2025 | |||
| BlackRock, Inc. | 1% | -86% | $1,359,774 | -$3,803,722 | 894,647 | -74% | BlackRock, Inc. | 30 Jun 2025 |
As of 30 Sep 2025, 75 institutional investors reported holding 71,298,009 shares of Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share (CABA). This represents 74% of the company’s total 96,015,846 outstanding shares.
The largest institutional shareholders of Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share (CABA) together control 70% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 10% | 9,677,125 | 0% | 1.5% | $22,644,473 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 9.2% | 8,829,758 | 0% | 0.03% | $20,661,634 |
| JENNISON ASSOCIATES LLC | 8.9% | 8,497,537 | +41% | 0.01% | $19,884,236 |
| T. Rowe Price Investment Management, Inc. | 8.7% | 8,362,489 | +23% | 0.01% | $19,569,000 |
| Cormorant Asset Management, LP | 5.2% | 5,000,000 | 0% | 0.81% | $11,700,000 |
| VANGUARD GROUP INC | 4.4% | 4,190,759 | +21% | 0% | $9,806,376 |
| Woodline Partners LP | 2.2% | 2,135,348 | +75% | 0.02% | $4,996,714 |
| HEIGHTS CAPITAL MANAGEMENT, INC | 2.2% | 2,084,202 | -34% | 1.6% | $4,877,033 |
| HEIGHTS CAPITAL MANAGEMENT, INC | 2.2% | 2,084,202 | -34% | 1.6% | $4,877,033 |
| BlackRock, Inc. | 1.7% | 1,620,872 | +67% | 0% | $3,792,840 |
| SUPERSTRING CAPITAL MANAGEMENT LP | 1.6% | 1,544,525 | +46% | 3.6% | $3,614,189 |
| MORGAN STANLEY | 1.5% | 1,474,676 | +11% | 0% | $3,450,742 |
| RENAISSANCE TECHNOLOGIES LLC | 1.4% | 1,339,423 | +962% | 0% | $3,134,250 |
| MARSHALL WACE, LLP | 1.4% | 1,326,043 | +594% | 0% | $3,102,942 |
| Alyeska Investment Group, L.P. | 1.4% | 1,300,000 | -73% | 0.01% | $3,042,000 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.3% | 1,294,949 | -41% | 0% | $3,031,000 |
| Schonfeld Strategic Advisors LLC | 1.1% | 1,044,169 | -30% | 0.02% | $2,443,353 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.96% | 920,340 | +66% | 0% | $2,154,082 |
| Opaleye Management Inc. | 0.84% | 808,882 | 0.27% | $1,892,784 | |
| CITADEL ADVISORS LLC | 0.73% | 705,465 | -58% | 0% | $1,650,788 |
| Burkehill Global Management, LP | 0.73% | 700,000 | -63% | 0.09% | $1,638,000 |
| MILLENNIUM MANAGEMENT LLC | 0.72% | 686,813 | -20% | 0% | $1,607,142 |
| JPMORGAN CHASE & CO | 0.56% | 537,649 | +565% | 0% | $1,258,098 |
| TWO SIGMA INVESTMENTS, LP | 0.49% | 470,475 | +86% | 0% | $1,100,911 |
| UBS Group AG | 0.42% | 405,120 | -14% | 0% | $947,982 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 102,548 | $224,503 | +$143,363 | $2.19 | 5 |
| 2025 Q3 | 71,298,009 | $166,850,266 | -$6,975,254 | $2.34 | 75 |
| 2025 Q2 | 72,777,604 | $110,698,611 | +$55,724,802 | $1.52 | 85 |
| 2025 Q1 | 36,304,416 | $50,331,609 | -$5,413,459 | $1.38 | 91 |
| 2024 Q4 | 38,433,072 | $87,226,012 | -$42,983,423 | $2.27 | 104 |
| 2024 Q3 | 48,049,164 | $226,748,702 | -$34,699,190 | $4.72 | 116 |
| 2024 Q2 | 50,801,335 | $379,995,301 | -$32,124,100 | $7.48 | 137 |
| 2024 Q1 | 51,050,542 | $870,921,299 | +$27,212,602 | $17.06 | 157 |
| 2023 Q4 | 48,539,586 | $1,101,850,659 | +$176,650,504 | $22.70 | 128 |
| 2023 Q3 | 40,903,546 | $622,571,929 | +$72,079,488 | $15.22 | 97 |
| 2023 Q2 | 36,440,182 | $470,450,874 | +$156,067,581 | $12.91 | 84 |
| 2023 Q1 | 24,651,946 | $203,869,260 | +$38,611,553 | $8.27 | 70 |
| 2022 Q4 | 19,878,011 | $183,868,921 | +$77,826,088 | $9.25 | 60 |
| 2022 Q3 | 11,928,226 | $7,751,081 | -$5,492,347 | $0.65 | 45 |
| 2022 Q2 | 16,803,742 | $17,812,960 | -$3,030,205 | $1.06 | 48 |
| 2022 Q1 | 18,183,343 | $36,877,990 | -$1,968,981 | $2.03 | 56 |
| 2021 Q4 | 18,168,410 | $68,859,189 | -$10,075,938 | $3.79 | 60 |
| 2021 Q3 | 17,375,298 | $211,265,514 | +$20,553,121 | $12.16 | 60 |
| 2021 Q2 | 15,752,840 | $135,465,315 | -$5,391,551 | $8.60 | 60 |
| 2021 Q1 | 16,228,404 | $180,131,214 | +$595,907 | $11.10 | 67 |
| 2020 Q4 | 16,173,259 | $201,828,469 | -$2,182,506 | $12.48 | 54 |
| 2020 Q3 | 16,353,879 | $177,273,014 | -$991,132 | $10.84 | 54 |
| 2020 Q2 | 16,442,959 | $183,160,097 | +$5,139,597 | $11.14 | 51 |
| 2020 Q1 | 16,009,620 | $116,871,000 | -$3,057,830 | $7.30 | 41 |
| 2019 Q4 | 16,265,458 | $227,227,000 | +$175,618,001 | $13.97 | 40 |