Security Snapshot

Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share (CABA) Institutional Ownership

CUSIP: 12674W109

13F Institutional Holders and Ownership History from Q4 2019 to Q1 2026

Latest Period

Q4 2025

Institutions Reporting

93

Shares (Excl. Options)

76,246,689

Price

$2.19

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Type / Class
Equity / Common Stock, par value $0.00001 per share
Symbol
CABA on Nasdaq
Shares outstanding
96,806,849
Price per share
$3.01
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
76,246,689
Total reported value
$166,934,120
% of total 13F portfolios
0%
Share change
+6,565,338
Value change
+$13,771,729
Number of holders
93
Price from insider filings
$3.01
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Quick Takeaways

  • CABA - Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share is tracked under CUSIP 12674W109.
  • 93 institutions reported positions in Q4 2025.
  • 12 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 93 to 12 between Q4 2025 and Q1 2026.
  • Reported value moved from $166,934,120 to $1,502,696.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 93 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 12674W109?
CUSIP 12674W109 identifies CABA - Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share (CABA) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
PRUDENTIAL FINANCIAL INC 8.9% +21% $29,447,817 +$5,132,486 12,584,537 +21% PRUDENTIAL FINANCIAL INC 30 Sep 2025
JENNISON ASSOCIATES LLC 8.9% +24% $29,447,817 +$5,797,046 12,584,537 +25% Jennison Associates LLC 30 Sep 2025
T. Rowe Price Investment Management, Inc. 10% -10% $21,589,583 -$1,099,531 9,858,257 -4.8% T. Rowe Price Investment Management, Inc. 31 Dec 2025
Bain Capital Life Sciences Opportunities III, LP 10% $15,483,400 9,677,125 Bain Capital Life Sciences Opportunities III, LP 30 Jun 2025
Cormorant Asset Management, LP 9.3% -7.1% $20,586,000 -$420,443 9,400,000 -2% Cormorant Asset Management, LP 31 Dec 2025
Adage Capital Management, L.P. 10% $14,404,128 9,002,580 Adage Capital Management, L.P. 30 Jun 2025
MILLENNIUM MANAGEMENT LLC 5.3% $15,494,904 5,130,763 Millennium Management LLC 11 Feb 2026
Alyeska Investment Group, L.P. 4.7% -23% $9,855,000 -$2,847,000 4,500,000 -22% Alyeska Investment Group, L.P. 31 Dec 2025
VANGUARD GROUP INC 3.8% $5,245,105 3,450,727 The Vanguard Group 30 Jun 2025
CITADEL ADVISORS LLC 3.4% -36% $7,371,644 -$3,903,787 3,150,275 -35% Kenneth Griffin 30 Sep 2025
Nichtberger Steven 3.3% $4,855,198 3,034,499 Nichtberger Steven 30 Jun 2025
BlackRock, Inc. 1% -86% $1,359,774 -$3,803,722 894,647 -74% BlackRock, Inc. 30 Jun 2025

As of 31 Dec 2025, 93 institutional investors reported holding 76,246,689 shares of Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share (CABA). This represents 79% of the company’s total 96,806,849 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share (CABA) together control 72% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
T. Rowe Price Investment Management, Inc. 10% 9,858,257 +18% 0.01% $21,590,000
Bain Capital Life Sciences Investors, LLC 10% 9,677,125 0% 1.6% $21,192,904
JENNISON ASSOCIATES LLC 9.2% 8,905,699 +4.8% 0.01% $19,503,481
ADAGE CAPITAL PARTNERS GP, L.L.C. 9.1% 8,829,758 0% 0.03% $19,337,170
VANGUARD GROUP INC 4.6% 4,419,458 +5.5% 0% $9,678,613
Cormorant Asset Management, LP 4.5% 4,400,000 -12% 0.55% $9,636,000
MILLENNIUM MANAGEMENT LLC 2.8% 2,736,912 +298% 0% $5,993,837
BlackRock, Inc. 2.4% 2,328,470 +44% 0% $5,099,349
SUPERSTRING CAPITAL MANAGEMENT LP 2.3% 2,253,550 +46% 2.6% $4,935,275
TWO SIGMA INVESTMENTS, LP 1.9% 1,839,799 +291% 0.01% $4,029,160
RENAISSANCE TECHNOLOGIES LLC 1.6% 1,522,583 +14% 0.01% $3,334,457
MORGAN STANLEY 1.4% 1,343,708 -8.9% 0% $2,942,720
Woodline Partners LP 1.3% 1,250,242 -41% 0.01% $2,738,030
Schonfeld Strategic Advisors LLC 1.2% 1,204,070 +15% 0.01% $2,636,910
PRICE T ROWE ASSOCIATES INC /MD/ 1.1% 1,093,959 -16% 0% $2,397,000
GEODE CAPITAL MANAGEMENT, LLC 1.1% 1,085,816 +18% 0% $2,378,961
MARSHALL WACE, LLP 0.99% 959,076 -28% 0% $2,100,376
Opaleye Management Inc. 0.93% 900,000 +11% 0.26% $1,971,000
Ikarian Capital, LLC 0.93% 900,000 0.26% $1,971,000
SCHRODER INVESTMENT MANAGEMENT GROUP 0.78% 756,637 0% $1,626,770
TWO SIGMA ADVISERS, LP 0.76% 737,900 +123% 0% $1,616,001
BURKEHILL GLOBAL MANAGEMENT, LP 0.72% 700,000 0% 0.1% $1,533,000
JANE STREET GROUP, LLC 0.68% 662,149 +533% 0% $1,450,107
Ensign Peak Advisors, Inc 0.57% 550,000 0% $1,204,500
KVP Capital Advisors, LP 0.52% 505,431 0% 1.1% $1,106,894

Institutional Holders of Cabaletta Bio, Inc. - Common Stock, par value $0.00001 per share (CABA) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 595,426 $1,502,696 +$9,008 $2.69 12
2025 Q4 76,246,689 $166,934,120 +$13,771,729 $2.19 93
2025 Q3 71,298,009 $166,850,266 -$6,956,298 $2.34 75
2025 Q2 72,777,604 $110,698,611 +$55,724,802 $1.52 85
2025 Q1 36,304,416 $50,331,609 -$5,413,459 $1.38 91
2024 Q4 38,433,072 $87,226,012 -$42,983,423 $2.27 104
2024 Q3 48,049,164 $226,748,702 -$34,699,190 $4.72 116
2024 Q2 50,801,335 $379,995,301 -$32,124,100 $7.48 137
2024 Q1 51,050,542 $870,921,299 +$27,212,602 $17.06 157
2023 Q4 48,539,586 $1,101,850,659 +$176,650,504 $22.70 128
2023 Q3 40,903,546 $622,571,929 +$72,079,488 $15.22 97
2023 Q2 36,440,182 $470,450,874 +$156,067,581 $12.91 84
2023 Q1 24,651,946 $203,869,260 +$38,611,553 $8.27 70
2022 Q4 19,878,011 $183,868,921 +$77,826,088 $9.25 60
2022 Q3 11,928,226 $7,751,081 -$5,492,347 $0.65 45
2022 Q2 16,803,742 $17,812,960 -$3,030,205 $1.06 48
2022 Q1 18,183,343 $36,877,990 -$1,968,981 $2.03 56
2021 Q4 18,168,410 $68,859,189 -$10,075,938 $3.79 60
2021 Q3 17,375,298 $211,265,514 +$20,553,121 $12.16 60
2021 Q2 15,752,840 $135,465,315 -$5,391,551 $8.60 60
2021 Q1 16,228,404 $180,131,214 +$595,907 $11.10 67
2020 Q4 16,173,259 $201,828,469 -$2,182,506 $12.48 54
2020 Q3 16,353,879 $177,273,014 -$991,132 $10.84 54
2020 Q2 16,442,959 $183,160,097 +$5,139,597 $11.14 51
2020 Q1 16,009,620 $116,871,000 -$3,057,830 $7.30 41
2019 Q4 16,265,458 $227,227,000 +$175,618,001 $13.97 40
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