Edward T. Mathers - Insider Trading & Ownership

Location
C/O Medimmune, Inc., One Medimmune Way, Gaithersburg, MD
Summary
The estimated net worth of Edward T. Mathers is at least $356M dollars as of October 6, 2025. Edward T. Mathers is the 10%+ Owner of Monte Rosa Therapeutics, Inc. and owns shares of Monte Rosa Therapeutics, Inc. (GLUE) stock worth about $146M. Edward T. Mathers is the 10%+ Owner of Savara Inc and owns shares of Savara Inc (SVRA) stock worth about $109M. Edward T. Mathers is the 10%+ Owner of Korro Bio, Inc. and owns shares of Korro Bio, Inc. (KRRO) stock worth about $61.1M. Edward T. Mathers is the Director, 10%+ Owner of MBX Biosciences, Inc. and owns shares of MBX Biosciences, Inc. (MBX) stock worth about $38.6M. Edward T. Mathers is the Director of RHYTHM PHARMACEUTICALS, INC. and owns shares of RHYTHM PHARMACEUTICALS, INC. (RYTM) stock worth about $769K. Edward T. Mathers is the Director of OnKure Therapeutics, Inc. and owns shares of OnKure Therapeutics, Inc. (OKUR) stock worth about $30K.
Signature
/s/ Zachary Bambach, attorney-in-fact
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Ownership of Edward T. Mathers

Symbol Company Relationship Holdings Value Past Year Net Change Change % Report Period
GLUE Monte Rosa Therapeutics, Inc. 10%+ Owner $146M Jun 28, 2021
SVRA Savara Inc 10%+ Owner $109M Jul 17, 2023
KRRO Korro Bio, Inc. 10%+ Owner $61.1M Apr 22, 2024
MBX MBX Biosciences, Inc. Director, 10%+ Owner $38.6M Jun 5, 2025
RYTM RHYTHM PHARMACEUTICALS, INC. Director $769K Jun 24, 2025
OKUR OnKure Therapeutics, Inc. Director $30K Sep 30, 2025
NEUE NeueHealth, Inc. Director, 10%+ Owner $0 -$24.5K -100% Oct 2, 2025
AKUS Akouos, Inc. Director Dec 1, 2022
INZY Inozyme Pharma, Inc. Director Jun 18, 2024
MIRM Mirum Pharmaceuticals, Inc. Director Jun 2, 2022
OBSV ObsEva SA Director Jan 1, 2023
SNTI Senti Biosciences, Inc. Director Jun 25, 2025
SYBX SYNLOGIC, INC. Director Jun 22, 2023
TRVI Trevi Therapeutics, Inc. Director Jun 11, 2025

Insider Transactions Reported by Edward T. Mathers:

Sym Company Class Transaction % Value $ * Price $ Shares Shares After Date Ownership
* An asterisk sign (*) next to the price indicates that the price is likely invalid.