J. JEFFERSON SMITH - 20 Jan 2026 Form 4 Insider Report for PRECISION BIOSCIENCES INC (DTIL)

Signature
/s/ Dario Scimeca Attorney-in-fact for Jeff Smith
Issuer symbol
DTIL
Transactions as of
20 Jan 2026
Net transactions value
-$41,106
Form type
4
Filing time
22 Jan 2026, 18:48:22 UTC
Previous filing
04 Jun 2025
Next filing
19 Feb 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
SMITH J. JEFFERSON Chief Research Officer C/O PRECISION BIOSCIENCES, INC., 302 E. PETTIGREW STREET, SUITE A-100, DURHAM /s/ Dario Scimeca Attorney-in-fact for Jeff Smith 22 Jan 2026 0001770169

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction DTIL Common Stock Options Exercise +2,500 +2.7% 93,718 20 Jan 2026 Direct F1, F2, F3
transaction DTIL Common Stock Options Exercise +10,447 +11% 104,165 20 Jan 2026 Direct F1, F2
transaction DTIL Common Stock Options Exercise +16,219 +16% 120,384 21 Jan 2026 Direct F1, F2
transaction DTIL Common Stock Sale $41,106 -10,200 -8.5% $4.03 110,184 21 Jan 2026 Direct F4
holding DTIL Common Stock 7,931 20 Jan 2026 By Charitable Remainder Unitrust

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction DTIL Restricted Stock Units Options Exercise $0 -2,500 -100% $0.000000 0 20 Jan 2026 Common Stock 2,500 Direct F2, F5
transaction DTIL Restricted Stock Units Options Exercise $0 -10,447 -50% $0.000000 10,447 20 Jan 2026 Common Stock 10,447 Direct F2, F6
transaction DTIL Restricted Stock Units Options Exercise $0 -16,219 -50% $0.000000 16,219 20 Jan 2026 Common Stock 16,219 Direct F2, F7
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.
F2 Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.
F3 Includes 3,413 shares acquired under the Issuer's 2019 Employee Stock Purchase Plan at a weighted average price per share of $5.74
F4 The sales were effected pursuant to a Rule 10b5-1 plan adopted on April 25, 2024. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.
F5 On January 20, 2023 the Reporting Person was granted RSUs, which vested in three substantially equal annual installments beginning on January 20, 2024, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.
F6 On April 18, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.
F7 On August 22, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.